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1.
Chinese Journal of Surgery ; (12): 115-117, 2008.
Article in Chinese | WPRIM | ID: wpr-237851

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the veracity of the C1 lateral mass screw insertion in the atlantoaxial fixation using plate and screw method without A-P fluoroscopic guiding.</p><p><b>METHODS</b>In the atlantoaxial fixation, without A-P fluoroscopic guiding, we probe lateral mass edge and identify the entrance point of C1 lateral mass screw indirectly. 159 patients treated with atlantoaxial fixation using plate and screw method were studied. Postoperative CT was used for analysis, and the position of the lateral mass screws in atlas was identified by coronary and axial CT scan. Three areas were delimited in and around the lateral mass of atlas in the axial CT scan, so as to analyze the location of screws: area A (inside the joint face), area B (outside the joint face but still in lateral mass), and area C (outside the lateral mass).</p><p><b>RESULTS</b>Among the 318 screws, 308 (96.9%) were located in area A, 5 in area B (1.6%), and 5 in area C (1.6%). All cases got atlantoaxial union at 4 months after operation.</p><p><b>CONCLUSION</b>Probing lateral mass edge and identifying the lateral mass indirectly is reliable for identifying the path of screw in atlas.</p>


Subject(s)
Adolescent , Adult , Aged , Child , Female , Humans , Male , Middle Aged , Atlanto-Axial Joint , General Surgery , Bone Screws , Cervical Atlas , General Surgery , Follow-Up Studies , Fracture Fixation, Internal , Methods , Joint Instability , General Surgery , Retrospective Studies , Spinal Fusion , Methods
2.
Chinese Medical Journal ; (24): 204-210, 2007.
Article in English | WPRIM | ID: wpr-273306

ABSTRACT

<p><b>BACKGROUND</b>Icariine is a flavonoid isolated from a traditional Chinese medicine Epimedium pubescens and is the main active compound of it. Recently, Epimedium pubescens was found to have a therapeutic effect on osteoporosis. But the mechanism is unclear. The aim of the study was to research the effect of Icariine on the proliferation and differentiation of human osteoblasts.</p><p><b>METHODS</b>Human osteoblasts were obtained by inducing human marrow mesenchymal stem cells (hMSCs) directionally and were cultured in the presence of various concentrations of Icariine. 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) test was used to observe the effect of Icariine on cell proliferation. The activity of alkaline phosphatase (ALP) and the amount of calcified nodules were assayed to observe the effect on cell differentiation. The expression of bone morphogenetic protein 2 (BMP-2) mRNA was detected by reverse transcriptase-polymerase chain reaction (RT-PCR).</p><p><b>RESULTS</b>Icariine (20 microg/ml) increased significantly the proliferation of human osteoblasts. And, Icariine (10 microg/ml and 20 microg/ml) increased the activity of ALP and the amount of calcified nodules of human osteoblasts significantly (P < 0.05). BMP-2 mRNA synthesis was elevated significantly in response to Icariine (20 microg/ml).</p><p><b>CONCLUSIONS</b>Icariine has a direct stimulatory effect on the proliferation and differentiation of cultured human osteoblast cells in vitro, which may be mediated by increasing production of BMP-2 in osteoblasts.</p>


Subject(s)
Humans , Alkaline Phosphatase , Bone Morphogenetic Protein 2 , Bone Morphogenetic Proteins , Genetics , Cell Differentiation , Cell Proliferation , Cells, Cultured , Drugs, Chinese Herbal , Pharmacology , Flavonoids , Pharmacology , Osteoblasts , Cell Biology , RNA, Messenger , Reverse Transcriptase Polymerase Chain Reaction , Transforming Growth Factor beta , Genetics
3.
Chinese Medical Journal ; (24): 216-218, 2007.
Article in English | WPRIM | ID: wpr-273304

ABSTRACT

<p><b>BACKGROUND</b>Lower cervical dislocation with locked facets is common in cervical injury. The locked facets include unilateral and bilateral types. Different successful closed reduction rates has been achieved between unilateral and bilateral types by using rapid skull traction, which was commonly used to reduce the cervical dislocation. It is important to investigate a suitable management specific to patients with different types of cervical locked facets.</p><p><b>METHODS</b>A total of 38 patients with cervical dislocation with locked facet due to cervical injury treated by rapid skull traction and operation from 1988 to 2005 were reviewed. Rapid skull traction was used in all the patients. Successful closed reduction rate was 88.0% in patients with bilateral cervical locked facets and that was 15.4% in those with unilateral cervical locked facets. These data were then statistically compared by Chi-square test. Patients who were reduced successfully underwent anterior cervical discectomy and fusion at the injured level, and those who failed in closed reduction received posterior open reduction and fixation.</p><p><b>RESULTS</b>In this series, there was statistically significant difference (P < 0.05) in the rate of successful closed skull traction reduction between unilateral and bilateral locked facets dislocation. Unilateral cervical locked facets dislocation was not easily reduced by skull traction which was suitable for reduction of bilateral cervical locked facets dislocation. However, unilateral cervical locked facets dislocation can be reduced by posterior open reduction.</p><p><b>CONCLUSIONS</b>Unilateral cervical locked facets dislocation should be treated immediately with posterior open reduction and instrumentation. Bilateral cervical locked facets dislocation can be reduced by rapid skull traction firstly and anterior cervical discectomy and interbody fusion later.</p>


Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Cervical Vertebrae , Wounds and Injuries , Diskectomy , Joint Dislocations , General Surgery , Spinal Fusion , Traction
4.
Chinese Journal of Surgery ; (12): 409-411, 2007.
Article in Chinese | WPRIM | ID: wpr-342157

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the qualitative diagnosis method of atlanto-axial tuberculosis and the corresponding therapeutic strategy.</p><p><b>METHODS</b>Twenty-two cases with atlanto-axial tuberculosis proven by histopathologic diagnosis were observed. Three cases and 17 cases underwent trans-oral biopsy and CT-guide percutaneous biopsy respectively, 2 cases were conformed by frozen section in operation. Thirteen of the 22 cases underwent surgical therapy: 1 case with anterior trans-oral radical eradication and fusion under Halo-vest immobilization, 7 cases with anterior cervical radical eradication, 1 case with anterior interbody fusion and titanic plate fixation, 2 cases were with posterior atlantoaxial interlaminar fusion and 2 cases with posterior cervical occipito-axial titanic plate internal fixation and fusion. Other 9 cases accepted nonsurgical therapy: 8 cases with Halo-vest immobilization and 1 case with head halter traction. All cases were given appropriate antituberculotic chemotherapy for 12-18 months.</p><p><b>RESULTS</b>All of the 22 cases were followed up, and the average time was 37 month. The lesion focus showed reparation and fusion in X-ray, and the results were satisfactory.</p><p><b>CONCLUSIONS</b>Biopsy can acquire the qualitative diagnosis on atlanto-axial tuberculosis. The choice of therapy is made on the situation of cold abscess, pathological fracture, atlanto-axial dislocation and spinal cord compression.</p>


Subject(s)
Adolescent , Adult , Child , Child, Preschool , Female , Humans , Male , Middle Aged , Antitubercular Agents , Therapeutic Uses , Atlanto-Axial Joint , Pathology , Biopsy, Needle , Methods , Follow-Up Studies , Fracture Fixation, Internal , Spinal Fusion , Tuberculosis, Spinal , Diagnosis , Pathology , Therapeutics
5.
Chinese Journal of Surgery ; (12): 801-804, 2006.
Article in Chinese | WPRIM | ID: wpr-300609

ABSTRACT

<p><b>OBJECTIVE</b>To explore the effect of early diagnosis of recurrence and early revision after resection of primary spine tumors.</p><p><b>METHODS</b>From March 1989 to September 2005, the relate clinic data of 55 patients with giant cell tumors, osteoblastomas, chondrosarcomas and chordomas in spine in big piecemeal and current fashion was analysed.</p><p><b>RESULTS</b>In 55 cases, 43 patients were followed up and had complete materials. The follow-up time ranged from 1.6 to 16.5 years, averagely 5.8 years. Thirty-four patients followed up regularly, and 12 were found recurrent, in which one C(1) giant cell tumor was found extensively large 3 months after initial surgery and was undertaken palliatory curet. The other eleven lesions were small and re-operated with wide margin. As a result, six patients lived without tumors during the 1 approximately 9.5 years follow-up, one patient gave up revision when found recurred again for economic reason, another four patients recurred repeatedly, but they persisted in regular follow-up and took revision surgeries whenever the recurred lesion were found. As a result, 3 of them lived without tumor and the other one died of other disease without sign of recurrence. In contrast, there were another nine patients who came to follow up until they had symptoms and were confirmed recurrent extensively. Two of them were excised radically for the tumors located in the relatively easily exposed segments of spine and lived without tumor now. While the other seven patients only received palliatory curet and all died of tumors.</p><p><b>CONCLUSIONS</b>Regular follow-up, early diagnosis of recurrence and early revision need to be regarded as part of radical excision and are very important of surgical treatment of spinal tumors, which can prolong the patients' survival time.</p>


Subject(s)
Adolescent , Adult , Aged , Child , Female , Humans , Male , Middle Aged , Early Diagnosis , Follow-Up Studies , Neoplasm Recurrence, Local , Diagnosis , General Surgery , Reoperation , Retrospective Studies , Spinal Neoplasms , Diagnosis , Pathology , General Surgery , Treatment Outcome
6.
Chinese Journal of Surgery ; (12): 843-847, 2006.
Article in Chinese | WPRIM | ID: wpr-300599

ABSTRACT

<p><b>OBJECTIVE</b>To determine the osteogenic capacity of autologous bone marrow mesenchymal stem cells (BMSCs)-calcium phosphate ceramic composites in vitro and implanted as a bone graft substitute for lumbar anterior interbody fusion in rhesus monkeys.</p><p><b>METHODS</b>From March 2003 to April 2005, 9 adult rhesus monkeys underwent lumbar L(3 - 4) and L(5 - 6) discectomy and interbody fusion via an anterior retroperitoneal approach. Two fusion sites in each animal were randomly assigned to two of three treatments: autogenous tricortical iliac crest bone graft (autograft group, n = 6) or cell-free ceramic graft (ceramic group, n = 6) or BMSCs-ceramic composite graft (BMSCs group, n = 6). Autologous BMSCs were culture-expanded and stimulated with osteogenic supplement. The cell-ceramic composites were constructed in a rotary dynamic cell culture system. The spinal fusion segments were evaluated by radiography, biomechanical testing, histologic analysis and histomorphometric analysis at 3 months post-surgery.</p><p><b>RESULTS</b>Biomechanical testing showed that spinal segments from the autograft group and the BMSCs-ceramic group were statistically and significantly stiffer than the cell-free ceramic group. The BMSCs-ceramic group and the autograft group showed equivalent biomechanical stiffness by statistical analysis. Histologically, both the autograft group and the BMSCs-ceramic group achieved osseous union, but the cell-free ceramic group had a fibrous union. Quantitative histologic analysis showed that the amount of bone formation was significantly greater in the autograft group and the BMSCs-ceramic group compared with the cell-free ceramic group. However, the amount of ceramic residue was significantly greater in the cell-free ceramic group versus the BMSCs-ceramic group.</p><p><b>CONCLUSIONS</b>The results indicate that BMSC-ceramic composites can enhance bone regeneration and achieve osseous spinal fusion 3 months after the implantation in rhesus monkey interbody fusion model. Cell-free ceramics has an unsatisfactory efficacy in spinal fusion due to its tense fibrous fusion.</p>


Subject(s)
Animals , Female , Male , Bone Regeneration , Bone Substitutes , Pharmacology , Calcium Phosphates , Ceramics , Macaca mulatta , Mesenchymal Stem Cells , Cell Biology , Spinal Fusion , Methods , Tissue Engineering
7.
Chinese Journal of Surgery ; (12): 238-241, 2006.
Article in Chinese | WPRIM | ID: wpr-317176

ABSTRACT

<p><b>OBJECTIVE</b>To study the clinical characteristics and treatment of flexion-distraction stage I injuries in subaxial cervical spine.</p><p><b>METHODS</b>Twelve cases of flexion-distraction stage I injuries with delayed symptoms, admitted in our hospital between January 1995 and December 2004, were studied retrospectively. In acute phase, all of 12 cases had neck pain and limited neck movements, neurological deficits were found in 6 of 12 cases. Eight cases had a correct diagnosis, and 2 cases had a error diagnosis, 2 cases missed. All cases were satisfactory by the primary conservative treatment. After 274 days average asymptomatic intervals, all of 12 cases had recurrence of neck pain, delayed neurological deficits were found in 10. MRI showed that all of 12 cases were unstable injuries.</p><p><b>RESULTS</b>All of the 12 patients were treated operatively. Decompression, fusion and fixation were performed by anterior approach in 9 cases, and by combined anterior and posterior approach in 3 cases. The average follow-up period was 33.1 months. Neck pain had great recovery in all cases, 10 cases with neurological deficits, 7 returned normal. Radiographic evidences of intervertebral bony fusion and good cervical alignment were observed in all of 12 cases.</p><p><b>CONCLUSIONS</b>Flexion-distraction stage I injuries is often caused by ligament and disc injuries, and often missed with subtle symptoms and radiographic changes. Inadequate primary treatment options are often due to failure to recognize the instability, and maybe result in delayed injuries. MRI is helpful for the early accurate evaluation of spinal stability. Unstable injury require early surgical treatment. The anterior approach operation is recommended to most of these patients with acute and old injuries. Combined anterior and posterior approach operation should be considered in these patients who have old injuries with stiff kyphosis.</p>


Subject(s)
Adult , Female , Humans , Male , Middle Aged , Bone Transplantation , Cervical Vertebrae , Wounds and Injuries , Diskectomy , Magnetic Resonance Imaging , Neck Pain , Retrospective Studies , Spinal Fusion , Spinal Injuries , Diagnosis , General Surgery , Time Factors
8.
Chinese Journal of Surgery ; (12): 201-204, 2005.
Article in Chinese | WPRIM | ID: wpr-345018

ABSTRACT

<p><b>OBJECTIVE</b>To determine the effectiveness of surgical correction for post-traumatic kyphosis of thoracolumbar spine.</p><p><b>METHODS</b>From 1996 to 2003, 33 consecutive patients with post-traumatic kyphosis of thoracolumbar spine were corrected surgically. The mean age was 40.3 years (range, 13 - 65 years). The mean time between the initial injury and surgical correction was 36.0 months (range, 6 - 220 months). The kyphotic deformity averaged 40.8 degrees (range, 20 degrees - 82 degrees ). All the patients had neurological deficits. Twelve patients had obvious back pain. Seven patients lost sphincter function completely and nineteen patients lost the function partly. Twenty-three patients had ever undergone laminectomy and/or instrumentation. The treatment procedure consisted of anterior release and posterior spinal osteotomy with instrumentation (15 patients), posterior closing wedge osteotomy with instrumentation (12 patients), anterior release and instrumentation (6 patients).</p><p><b>RESULTS</b>Kyphosis was corrected from an average of 40.8 degrees to an average of 5.7 degrees, the corrective rate was 86.0% (40.8 degrees - 5.7 degrees /40.8 degrees). There were no severe complications. The average follow-up period was 24.6 months (range, 6 - 84 months). There was no loss of correction at follow-up. Ten of these patients showed an improvement in neural function by one or two levels according to the classification. Sphincter function recovered partly in ten patients. Back pain was relieved significantly in all of twelve patients with back pain preoperatively. Bony fusion was achieved in thirty-two patients. One patient had nonunion and achieved bony fusion after revision.</p><p><b>CONCLUSION</b>Posterior closing wedge osteotomy was suitable to kyphosis less than 40 degrees. Anterior release and posterior spinal osteotomy was effective, especially to the patients with severe kyphosis deformity or with operation history. Patients with incomplete neurological deficits and/or severe back pain could get benefit from osteotomy of spine, even if their medical history was long.</p>


Subject(s)
Adolescent , Child , Female , Humans , Male , Middle Aged , Bone Transplantation , Kyphosis , General Surgery , Lumbar Vertebrae , Wounds and Injuries , General Surgery , Osteotomy , Methods , Retrospective Studies , Spinal Fractures , General Surgery , Spinal Fusion , Thoracic Vertebrae , Wounds and Injuries , General Surgery , Treatment Outcome
9.
Chinese Journal of Surgery ; (12): 221-224, 2005.
Article in Chinese | WPRIM | ID: wpr-264537

ABSTRACT

<p><b>OBJECTIVE</b>To find the causes of the spinal primary tumors recurrence in surgical technique.</p><p><b>METHODS</b>From 1989 to 2002, 38 cases of primary spine tumors, including giant cell tumor, osteoblastoma, chondrosarcoma and chordoma with wide resection via a piece-meal fashion. By adopting a retrospective method, the present study investigated the clinical and imaging materials of pre- and post-operation period and those in follow-up.</p><p><b>RESULTS</b>The study included 18 cases of giant cell tumor, 6 osteoblastoma, 6 chondrosarcoma and 8 chordoma. In all cases, 63% of tumors were in cervical and cervicothoracic (C(7)-T(2)) spine; 29% in thoracolumbar (T(4)-L(5)) spine and 8% in sacrum. Tumors involved in multi-segment were 34%. And 71% patients had the tumor in the body and the arch simultaneously. And 71% of tumors formed paraspinal masses, 42% in both sides. The tumors invaded the channel in 58% of the cases. The compartment were invaded in 79% patients. Finally, 32 patients were followed up, from 1.0 approximately 14.9 years, 5.1 years average. Seventeen patients recurred after the surgery, the recurrence rate was 53%. The recurrence rate of giant cell tumor was 35%, osteoblastoma 50%, chondrosarcoma 75%, chordoma 100%. The recurrence rate of tumor in cervical and cervicothoracic spine was 63%, thoracic-lumbar 33%, sacrum 67%. The recurrence rate of multi-segment tumors was 80%, and that of single segment 41%. The recurrence rate of the tumors involving in vertebral body alone or involving the arch simultaneously reached 75% and 55% respectively; the recurrent rate in the arch alone was 33%. The recurrence rate of the tumors involving in vertebral body ranged in different segments. Those growing in cervical and cervicothoracic spine reached 73%; those growing in thoracolumbar spine was only 25%. The recurrence of the tumors without soft masses was 20%, those of single-sided soft masses was 45% and those of double-sided 91%. Among the 17 recurrent patients, 83% of the tumors were in the cervical and cervicothoracic spine. Those extending to the upper cervical and cervicothoracic amounted to 58%. All the 17 recurrent patients had body lesion and paraspinal soft masses.</p><p><b>CONCLUSIONS</b>During the primary spinal tumor operation, that failure to get adequate exposure and full division is thought to be the cause of recurrence. So the precise design before surgery and adequate exposure of the tumor in the surgery is the guarantee of wide excision.</p>


Subject(s)
Adolescent , Adult , Aged , Child , Female , Humans , Male , Middle Aged , Neoplasm Recurrence, Local , Retrospective Studies , Spinal Neoplasms , Pathology , General Surgery , Treatment Outcome
10.
China Journal of Chinese Materia Medica ; (24): 289-291, 2005.
Article in Chinese | WPRIM | ID: wpr-279175

ABSTRACT

<p><b>OBJECTIVE</b>To study the effects of epimedium pubescens icariine on the proliferation and differentiation of human osteoblasts.</p><p><b>METHOD</b>Human osteoblasts were obtained by inducting human marrow mesenchymal stem cells (hMSCs) directionally. MTT was used to observe the proliferation and activity of ALP was assayed to observe the differentiation of the third passage human osteoblasts cultured in vitro. The expression of BMP-2 mRNA was checked by RT-PCR.</p><p><b>RESULT</b>Epimedium pubescens icariine at the dose of 20 microg x mL(-1) increased greatly the proliferation and differentiation of human osteoblasts and promoted the expression of BMP-2 mRNA.</p><p><b>CONCLUSION</b>Epimedium pubescens icariine enhances significantly the proliferation and differentiation of human osteoblasts, which may be mediated by increasing the expression of BMP-2 mRNA.</p>


Subject(s)
Humans , Bone Morphogenetic Protein 2 , Bone Morphogenetic Proteins , Genetics , Cell Differentiation , Cell Proliferation , Epimedium , Chemistry , Flavonoids , Pharmacology , Osteoblasts , Cell Biology , Plants, Medicinal , Chemistry , RNA, Messenger , Genetics , Transforming Growth Factor beta , Genetics
11.
Chinese Journal of Surgery ; (12): 707-711, 2004.
Article in Chinese | WPRIM | ID: wpr-299885

ABSTRACT

<p><b>OBJECTIVE</b>To observe the clinical effect of a occipitocervical fixation systems using C(2) pedicle screws and plates.</p><p><b>METHODS</b>An occipitocervical fixation system was designed. Since June 2001 to March 2003, 38 patients with instability of atlantoaxial joint underwent reconstructive surgery using this systems. Twenty-four patients were associated with congenital occipitalization. The pedicle screws were inserted into C(2) pedicles in the direction as its axis. The occipitocervical plate was slightly bent to fit the occipital contour and fixed onto the occiput. Hyperflexion alignment of the occipitoatlantoaxial complex was corrected by application of extensional force created by tightening of the nut on the pedicle screws. The autogenous cancellous bones were grafted between the occiput and the axis.</p><p><b>RESULTS</b>In this series, neither vertebral artery nor spinal cord was injured. 36 of 38 cases were followed up for an average of 18 months, all cases achieved solid bony fusion. No implant failure was found.</p><p><b>CONCLUSIONS</b>Occipitocervical reconstruction by the combination of C(2) pedicle screws and occipitocervical plate systems can provide sufficient correction of malalignment in the occipitoatlantoaxial region and achieve high fusion rate.</p>


Subject(s)
Adolescent , Adult , Child , Female , Humans , Male , Middle Aged , Atlanto-Axial Joint , General Surgery , Bone Plates , Bone Screws , Cervical Vertebrae , General Surgery , Follow-Up Studies , Joint Instability , General Surgery , Occipital Bone , General Surgery , Plastic Surgery Procedures , Methods , Spinal Fusion , Methods , Treatment Outcome
12.
Chinese Journal of Surgery ; (12): 716-719, 2004.
Article in Chinese | WPRIM | ID: wpr-299883

ABSTRACT

<p><b>OBJECTIVE</b>To study the causes of failure following surgical treatment of lumbar spondylolisthesis, procedures for redo surgery and the final result of reoperation.</p><p><b>METHODS</b>20 patients who had a repeat operation for lumbar spondylolisthesis were studied retrospectively. On average 24.3 months following the previous surgery, all of these patients had recurrence or progression of back and leg pain. All of 20 patients were reoperated by means of three different procedures.</p><p><b>RESULTS</b>The causes of failure were post-operative destabilization (6 cases); progressive spondylolithesis (3 cases) implants failure (10 cases) and mistake segment (one case). After reoperation, a mean 34.1 months' follow-up was made. The excellent or good rate was 90%. Incorporation of graft was found in 18 cases with fusion by inter-transverse process and 2 cases by intervertebral space. New bone formation was found in 6 out of 8 cases that had a simultaneous intervertebral cage implant. No implant failure was found in all patients.</p><p><b>CONCLUSIONS</b>Simple laminectomy or discectomy was not indication for lumbar spondylolithesis. No bone graft or union was the main causes of implant failure. Posterior instrumented fusion with laminectomy decompression can be used in the patients who had a prior surgery of simple discectomy or anterior intervertebral bone graft. Except for posterior instrumented fusion with extensive laminectomy decompression, Intervertebral fusion should be considered in the patients who had a prior surgery of laminectomy decompression with instrument, anterior intervertebral fusion (ALIF) was recommended for these cases.</p>


Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Bone Transplantation , Methods , Decompression, Surgical , Diskectomy , Methods , Follow-Up Studies , Lumbar Vertebrae , General Surgery , Reoperation , Retrospective Studies , Spinal Fusion , Methods , Spondylolisthesis , General Surgery , Treatment Outcome
13.
Chinese Journal of Surgery ; (12): 1481-1484, 2004.
Article in Chinese | WPRIM | ID: wpr-345061

ABSTRACT

<p><b>OBJECTIVE</b>To observe the relationship of adjacent segment degeneration and neck symptom after anterior cervical fusion.</p><p><b>METHODS</b>Making follow-up to 66 cases who had accepted anterior cervical fusion for 1 - 16 years, average 10.5 years. Observe the mobilization and gliding degree of adjacent segment in flexion-extension X-ray film, neck symptom, and the relationship of them. In 59 of these patients, the mobilization of entire cervical spine and non-fusion segment was observed before/after operation.</p><p><b>RESULTS</b>The incidence of adjacent segment instability in follow-up term was 72.7%, and 40.9% of all patients had significant neck symptom. The rate of significant neck symptom in patients who had instability was 48%, whereas which in patients without instability was 18.8%, and the difference was statistically significant (P < 0.05). The difference of mild instability and severe instability was not statistically significant (P > 0.1). The mobilization of entire cervical spine decreased obviously (P < 0.001). The mobilization of adjacent segment increased obviously (P < 0.01), and which of non-adjacent segment had no change (P > 0.05).</p><p><b>CONCLUSION</b>Majority of patients who have accepted anterior cervical fusion possessed instability of adjacent segment, but many of them have no symptoms. Adjacent segment instability is one of the reasons that induce neck symptoms.</p>


Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Cervical Vertebrae , Physiology , General Surgery , Follow-Up Studies , Joint Instability , Therapeutics , Range of Motion, Articular , Spinal Diseases , Therapeutics , Spinal Fusion
14.
Chinese Journal of Surgery ; (12): 1174-1177, 2004.
Article in Chinese | WPRIM | ID: wpr-345105

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the efficacy of allogenic strut bone graft and instrumentation for anterior cervical fusion following subtotal corpectomy and decompression in cervical myelopathy.</p><p><b>METHODS</b>Thirty-five patients with cervical myelopathy were treated by the procedure of allogenic strut bone graft and instrumentation for anterior cervical fusion following subtotal corpectomy and decompression. The preoperative average JOA scale score was 8.7 point (Range 4-15).</p><p><b>RESULTS</b>Sixty-nine vertebral were corpectomized and 104 levels were decompressed and fused with an average of 3 levels. Among the cases, 1 vertebrae was corpectomized in 7 cases, 2 vertebra in 22 cases, 3 vertebra in 6 cases. There were no surgery-related complications. The patients were followed up from 11-37 months, with an average of 17.4 months. No plate breakage, screw loose, graft infection, lysis and absorption was discovered. The fusion rate was 100%, the average time of fusion was 9.3 months (range from 6-15 months). The postoperative average JOA scale score was 14.8 point (range 7-17), the recovery ratio was 73.5% and the excellent and good results was 82.8%.</p><p><b>CONCLUSIONS</b>The use of allogenic strut bone graft and instrumentation for anterior cervical fusion following subtotal corpectomy and decompression in cervical myelopathy may not only simplify surgical procedure and decrease injuries and complications, but also the fusion is satisfactory and reliable.</p>


Subject(s)
Female , Humans , Male , Bone Transplantation , Cervical Vertebrae , General Surgery , Follow-Up Studies , Laminectomy , Spinal Fusion , Spinal Osteophytosis , General Surgery , Transplantation, Homologous , Treatment Outcome
15.
Chinese Journal of Surgery ; (12): 1182-1184, 2004.
Article in Chinese | WPRIM | ID: wpr-345103

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the character, diagnosis and treatment of multiple-level fractures of the cervical spine.</p><p><b>METHODS</b>Forty-three patients (38 male, 5 female) with multiple-level fractures of the cervical spine were retrospectively analysed in our hospital from 1988-2001.</p><p><b>RESULTS</b>Among 36 patients with multiple contiguous fractures of the cervical spine, 32 cases were injured at low cervical spine; 7 patients were non-contiguous spinal fractures in which there were 5 cases injured at upper and lower cervical spine. The frequently injured sites were vertebral body (31 patients), laminae (25 patients), spinous process (9 patients), vertebral arch (4 patients), transverse process (5 patients), lateral mass (5 patients); level frequently affected were C(4), C(5), C(6) and C(7); 21 patients were treated with anterior vertebrectomy and fusion, 10 patients with posterior laminectomy and fixation, 2 patients with both anterior and posterior decompression and fixation. 60.5% were flexion-compression injury. 10 patients with conservative treatment.</p><p><b>CONCLUSIONS</b>Contiguous type was more common than non-contiguous type in multiple level cervical spinal fractures; Injured sites always located at lower cervical spine in contiguous cervical fractures different from that fractures of atlas, axis and lower cervical spine in non-contiguous type; Unstable segments and level of spinal cord injury were at lower cervical spine; Operations must obtain both decompression and stability of spine.</p>


Subject(s)
Adolescent , Adult , Female , Humans , Male , Middle Aged , Cervical Vertebrae , Wounds and Injuries , General Surgery , Follow-Up Studies , Laminectomy , Multiple Trauma , Diagnosis , General Surgery , Therapeutics , Retrospective Studies , Spinal Fusion , Spinal Injuries , Diagnosis , General Surgery , Therapeutics
16.
Chinese Journal of Surgery ; (12): 286-288, 2003.
Article in Chinese | WPRIM | ID: wpr-300065

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the mechanism of Hangman's fracture and its clinical manifestation and treatment.</p><p><b>METHODS</b>Ten patients with Hangman's fracture treated at our hospital from 1988 to 2001 were analysed.</p><p><b>RESULT</b>Patients were injured by motor vehicle accidents (7 patients), object hitting on the head (1), and fall (1). Injuries were classified as type I (1 patient), type II (5), type IIa (2) and type III (2).</p><p><b>CONCLUSIONS</b>Motor vehicle accident and fall are major causes of Hangman's fracture with neurological deficits but limited motion and neck pain. Hangman's fracture is easily diagnosed using lateral cervical X-ray and CT. Hangman's fractures of types I, II and IIa can be treated conservatively, but those of type III or spinal cord injury require surgical stabilization.</p>


Subject(s)
Adolescent , Adult , Female , Humans , Male , Middle Aged , Young Adult , Axis, Cervical Vertebra , Wounds and Injuries , Follow-Up Studies , Fracture Fixation , Retrospective Studies , Spinal Fractures , Diagnosis , General Surgery , Spinal Fusion , Traction
17.
Chinese Journal of Surgery ; (12): 441-444, 2003.
Article in Chinese | WPRIM | ID: wpr-300012

ABSTRACT

<p><b>OBJECTIVE</b>To introduce the application of Ilizarov technique in ankle fusion with serious pathology and failed ankle arthrodesis.</p><p><b>METHOD</b>The medical records and images of 9 cases of complex ankle fusion using Ilizarov external fixator were analyzed. Among the 9 cases, 6 received revisional ankle fusion, and 3 primary fusion for septic arthritis. All the cases were followed up for an average of 18.1 months.</p><p><b>RESULTS</b>Six cases showed good results, i.e, no or mild pain, occasional limp and stable fusion and 3 cases fair results, i.e, moderate pain, persistent limp or occupational restriction, and stable fusion.</p><p><b>CONCLUSION</b>Ilizarov technique is one of the effective method for the treatment of complex ankle arthrodesis.</p>


Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Ankle Joint , General Surgery , Arthrodesis , Methods , Ilizarov Technique , Salvage Therapy
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